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PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
Descriptors Found:
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DeCS
Descriptor
English
:
Protein Tyrosine Phosphatase, Non-Receptor Type 1
Descriptor
Spanish
:
Proteína Tirosina Fosfatasa no Receptora Tipo 1
Descriptor
Portuguese
:
Proteína Tirosina Fosfatase não Receptora Tipo 1
Tree Number:
D08.811.277.352.650.775.300.100
D12.644.360.585.100
D12.776.476.564.100
Definition
English
:
A subtype of non-receptor
protein tyrosine phosphatases
that includes two distinctive targeting motifs; an N-terminal motif specific for the
INSULIN
RECEPTOR, and a C-terminal motif specific for the SH3 domain containing
proteins
. This subtype includes a hydrophobic domain which localizes it to the
ENDOPLASMIC RETICULUM.
History Note
English
:
2008
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52696
Unique Identifier:
D054562
Occurrence in VHL
:
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